The science, in plain sight.
No black box. Here is exactly how inflammation compounds into the way you feel — and how the right repair runs it in reverse.
How a leaky gut quietly becomes a tired body.
When the gut barrier weakens, bacterial fragments can enter the bloodstream. The immune system reacts, inflammation spreads body-wide, and it wears down the mitochondria that power your cells — which can fuel still more inflammation.1,2,3 This is the biological pathway the measurement system is designed to track.
- Camilleri M. Leaky gut: mechanisms, measurement and clinical implications in humans. Gut. 2019;68(8):1516–1526. doi:10.1136/gutjnl-2019-318427
- Fasano A. All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases. F1000Research. 2020;9:69. doi:10.12688/f1000research.20510.1
- Li Y, Berliocchi L, Li Z, Rasmussen LJ. Interactions between mitochondrial dysfunction and other hallmarks of aging: paving a path toward interventions that promote healthy old age. Aging Cell. 2024;23(1):e13942. doi:10.1111/acel.13942
Modern life keeps the fire lit.
Everyday pressures — especially here — that quietly feed chronic inflammation.
Your biology hasn’t changed in millennia; your environment has. These are the forces measurably pushing inflammation up, day after day.
Ultra-processed food
Chronic stress
Too little sleep
Sedentary days
Environmental load
Gut disruptors
- Lane MM, Gamage E, Du S, et al. Ultra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses. BMJ. 2024;384:e077310. doi:10.1136/bmj-2023-077310
- Rosengren A, Hawken S, Ôunpuu S, et al. Association of psychosocial risk factors with risk of acute myocardial infarction in 11 119 cases and 13 648 controls from 52 countries (the INTERHEART study): case-control study. The Lancet. 2004;364(9438):953–962. doi:10.1016/S0140-6736(04)17019-0
- Cappuccio FP, Cooper D, D’Elia L, Strazzullo P, Miller MA. Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies. European Heart Journal. 2011;32(12):1484–1492. doi:10.1093/eurheartj/ehr007
- Ekelund U, Steene-Johannessen J, Brown WJ, et al. Does physical activity attenuate the association of sitting time with mortality? A harmonised meta-analysis of data from more than 1 million men and women. The Lancet. 2016;388(10051):1302–1310. doi:10.1016/S0140-6736(16)30370-1
- World Health Organization. Billions of people still breathe unhealthy air: new WHO data. Geneva: WHO; 2022.
- Palleja A, Mikkelsen KH, Forslund SK, et al. Recovery of gut microbiota of healthy adults following antibiotic exposure. Nature Microbiology. 2018;3(11):1255–1265. doi:10.1038/s41564-018-0257-9
Belief needs proof. Proof needs a method.
Understanding the biology is only half of it. The other half is measuring it — repeatably, from routine lab markers, the same way every time.
Science built to global standards.
Developed with research partners, registered with the FDA, and supported by USAID-funded work, our measurement approach uses accessible laboratory markers to keep the science grounded and repeatable.